Jefferson University Hospitals


If you would like to restore fullness and elasticity to your skin, Juvederm™ may be an appropriate treatment.

What Does Juvederm Involve?

Juvederm is a smooth gel made of hyaluronic acid, a substance that occurs naturally in your skin and helps to add volume and hydration. Our physicians are experts in injecting the gel under your skin to instantly restore volume and smooth away wrinkles and folds.

Juvederm provides a smooth, natural look and feel. Juvederm is the first hyaluronic acid dermal filler that is proven to be safe and effective for persons of color.

Juvederm injections are available at:

  • The Herbert Kean Center for Facial Aesthetics
  • The Laser Surgery and Cosmetic Dermatology Center
  • The Facial Rejuvenation Program

How Long Does Juvederm Last?

The results last six to 12 months and potentially longer. They can be injected during sessions from 15 to 30 minutes.

Other Injectable Fillers

Restylane®, Perlane®, Belotero®, Radiesse® and Sculptra® are all injectable fillers that restore facial volume and soften the appearance of wrinkles.

The use of fillers is sometimes called "liquid facelifts" because of the potential facelift-like results they produce. Fillers are an excellent nonsurgical way to rejuvenate your face, but are not a replacement for a facelift. Fillers help restore the volume in your face that is lost over time.

These injectable fillers are offered by the Jefferson Laser Surgery and Cosmetic Dermatology Center.

Restylane, Perlane, Juvederm and Belotero

Restylane (Medicis), Perlane (Medicis) and Belotero(Merz) are products containing naturally occurring hyaluronic acid. The results last six to 12 months and potentially longer. They can be injected during sessions lasting from 15 to 30 minutes and can erase wrinkles, eliminate some scars and augment or contour the lips and cheeks.

Recent developments in soft-tissue augmentation have focused on volume replacement. We now understand that many changes previously attributed to sagging tissue are, in fact, caused by loss of fat and facial volume.

Two types of major wrinkles can also be treated with hyaluronic acid products. They are the "smile line" (or dynamic wrinkle) and the static wrinkle, caused by aging, overexposure to the sun and/or cigarette smoking. These injectable products are often used to treat furrows that develop between the eyebrows (glabellar wrinkles), wrinkles around the eyes (periorbital wrinkles), lines that run from the nose to the corner of the mouth (nasolabial folds) and acne scars. They are also used to augment thin lips, fill in sunken areas on the cheeks or chin, and correct the sad expression lines that may appear at the corners of the mouth (marionette lines).

Recent advancements now allow us to fill in hollows and dark circles under the eyes, and the results can be dramatic.

Most of these hyaluronic acid products contain an anesthetic, so supplemental pain medication is rarely necessary. Occasionally, particularly when treating the lips, our physicians will use a topical or local anesthetic to make the procedure more comfortable.


Radiesse (Merz) is calcium hydroxylapatite, and it an ideal product for volume replacement and improvement of deep wrinkles. Radiesse produces results that last from 12 to 18 months. Patients who seek long-lasting volume replacement are often good candidates. Radiesse can also be used in the hands for long-term rejuvenation.


Sculptra is a synthetic poly-L-lactic acid. Sculptra is used by our physicians primarily for volume replacement, and it provides unparalleled results. Sculptra is approved by the FDA for treatment of facial wrinkles, folds and fat loss. It can produce marked improvements in cheek hollows, create a sharper jawline, fill in hollow temples and achieve a more natural and youthful look overall through carefully placed injections.

Sculptra is different from other fillers in that results are not immediate, but rather takes time to see. It may appear that the filler worked immediately because of swelling and water that is added to Sculptra to facilitate injection. In a few days, when the swelling goes down and the water is absorbed by your body, you may look just like you did before your treatment. This is because Sculptra takes time to gradually correct the creases and folds in your skin.

Additional treatments are usually performed after six to eight weeks, and patients usually require two to four treatments before seeing optimal results. How long the results last differs from person to person. In one clinical study, Sculptra's effects lasted for up to two years, but touch-up treatments are often needed to maintain the desired results.