Jefferson University Hospitals

Intracytoplasmic Sperm Injection (ICSI)

Performed only as a component of some in vitro fertilization (IVF) treatments, intracytoplasmic sperm injection is a procedure in which each egg in culture is injected with an individual sperm in order to improve fertilization rates.

ICSI is often effective in generating healthy embryos even for men with low or immotile sperm in the ejaculate or using sperm obtained surgically from the testes/epididymis. ICSI may also be advised when there are limiting numbers of mature eggs at the time of retrieval or for couples pursuing preimplantation genetic screening of their embryos including comprehensive chromosome screening.

If you are trying to conceive, the fertility specialists at Reproductive Medicine Associates (RMA) at Jefferson in Philadelphia may recommend intracytoplasmic sperm injection to increase your chance of pregnancy.

What Does Intracytoplasmic Sperm Injection Involve?

Intracytoplasmic sperm injection is a procedure used to enhance the fertilization of eggs during some in vitro fertilization (IVF) treatments. After the eggs are retrieved, each egg is injected with an individual sperm; this procedure maximizes the chances of fertilization even in settings of very low sperm counts, low sperm motility or poor sperm morphology (shape).

ICSI can be performed using donor sperm.

Why Choose RMA at Jefferson for Intracytoplasmic Sperm Injection?

Your RMA at Jefferson doctor will counsel you regarding the possible indications and benefits of ICSI as you prepare for your IVF treatment. Our highly skilled embryologists are experts at performing ICSI and work with our physicians to ensure the highest possible success rates for our patients.

Schedule an Appointment with a Fertility Expert

To schedule an appointment with one of our fertility specialists, please call 215-922-1556.

Flexible financing options, a refund guarantee program, military and first-responder discounts, and financial aid programs each aim to make our world-class care as widely available as possible. To reach out to a financial counselor, please e-mail