Jefferson University Hospitals

Endometrial Biopsy

If your gynecologist wants to check for the presence of abnormal cells or cancer, an endometrial biopsy may be recommended in the following cases:

  • You are having difficulty conceiving a child
  • You are experiencing bleeding after menopause
  • There is an absence of uterine bleeding
  • You are having abnormal menstrual bleeding
  • You are undergoing hormone replacement therapy

What Does Endometrial Biopsy Involve?

An endometrial biopsy is a procedure performed at Jefferson to obtain a small tissue sample from the lining of the uterus, called the endometrium. After the biopsy, the endometrial tissue is examined under a microscope to identify the presence of abnormal cells, or the effects of hormones on the endometrium.