Jefferson University Hospitals


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If you or a loved one has been diagnosed with a glioma (a type of brain tumor), turn to the multidisciplinary clinical team at Jefferson. Jefferson physicians are among the most experienced in the nation for the treatment of this condition, participating in national trials and strategic initiatives from the National Cancer Institute.

Malignant gliomas are the most frequently diagnosed primary brain tumor, and the prognosis for patients has been poor. A challenge for physicians is how to employ the most powerful combination of surgery, radiation and chemotherapy while preserving brain function. Quality of life is an especially crucial goal when patients are facing the possibility of limited survival time.

New Glioma Treatment Options

A new treatment offered at the Brain Tumor Center of the Kimmel Cancer Center at Jefferson is using hypofractionated stereotactic radiation therapy (H-SRT) to improve outcomes for patients with recurrent high-grade gliomas.

For the past 15 years, Jefferson has been a leader in pioneering the use of H-SRT for brain tumors, as documented by widely published research. One recent multidisciplinary study, published in the Journal of Clinical Oncology, points to the important role that H-SRT can play in treating recurrent glioblastomas.

Jefferson researchers have discovered the following:

  • H-SRT is an effective tool for extending survival time. It resulted in a median survival time of 11 months after the start of treatment.
  • It allows patients with recurrent disease to avoid the side effects commonly associated with chemotherapy, the drain of follow-up surgery or other, more time-consuming radiation therapy.
  • Patients who experienced recurrence within six months after initial treatment had an excellent response, which suggests that such patients should not be disqualified from H-SRT.

A multidisciplinary team including neurosurgeons, neuropathologists, neuro-oncologists, radiation oncologists and neuro-immunologists will soon launch a novel immunotherapy trial unique to Jefferson for the treatment of patients with malignant gliomas.

Make an Appointment

Call 1-800-JEFF-NOW (1-800-533-3669) to make an appointment with a glioma specialist.