Jefferson University Hospitals

Types of Cutaneous Lymphoma

T-cell cutaneous lymphoma is the most common of the numerous subtypes of cutaneous lymphoma. Within that group, there are even more subtypes.

T-Cell Cutaneous Lymphoma

The numerous subtypes of cutaneous T-cell lymphomas include:

Mycosis Fungoides – This subtype accounts for nearly half of all cutaneous lymphomas. It first appears on the skin, and it can spread to the lymph nodes or other organs such as the spleen, liver or lungs.

Sézary Syndrome – This subtype is more aggressive than mycosis fungoides and involves all of the skin.

Anaplastic Large T-Cell Lymphoma – This aggressive subtype starts as a tumor on the skin, then may spread to the lymph nodes, bones, soft tissues, lungs or liver.

Lymphomatoid Papulosis – This subtype affects younger adults and will sometimes heal without treatment.

Primary Cutaneous CD8+ T-Cell Lymphoma – This subtype can look like mycosis fungoides.

Parapsoriasis – This subtype starts with scaly patches on the skin that can sometimes progress to cutaneous lymphoma.

Subcutaneous Panniculitis-Like T-Cell Lymphoma – This subtype is a rare form of cancer that invades the skin’s deepest layers.

Primary Cutaneous Peripheral T-Cell Lymphoma, Unspecified – This subtype is a category for rare, unspecified types of cutaneous T-cell lymphomas.

B-Cell Cutaneous Lymphoma

Cutaneous B-cell lymphoma accounts for about one in five cutaneous lymphoma cases. There are also several subtypes of cutaneous B-cell lymphomas. These include:

Cutaneous Follicle Center Lymphoma – This is the most prevalent B-cell subtype. It grows very slowly and is diagnosed more often in middle-aged adults

Cutaneous Marginal Zone B-Cell Lymphoma – This is the second most prevalent B-cell lymphoma, and it is often found on the arms. It can be diagnosed at any age.

Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type – This subtype is a more rare but more aggressive lymphoma, and it usually is found on the legs. It is diagnosed more often in women than in men.

Primary Cutaneous Diffuse Large B-Cell Lymphoma, Other – This subtype is also more rare and can be found anywhere but the leg.

Make an Appointment

Call the Cutaneous Lymphoma Center at 215-955-9295 or 1-800-JEFF-NOW (1-800-533-3669) to make an appointment.