Jefferson University Hospitals


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If you or a loved one is diagnosed with cholangitis, turn to the physicians at Jefferson Hospitals in Philadelphia. Our physicians are experienced in treating patients who have biliary system disorders, such as cholangitis, to help reduce inflammation of the bile duct or clear an obstruction.

Cholangitis is an inflammation of the bile duct system that is usually related to a bacterial infection. The primary cause of cholangitis is an obstruction or blockage somewhere in the bile duct system. The blockage may be from stones, a tumor, blood clots, a narrowing that may occur after a surgical procedure, swelling of the pancreas, or from parasite invasion. Other causes include a backflow of bacteria from the small intestine, a blood infection (bacteriemia), or following a diagnostic procedure such as an endoscopic examination. The infection causes pressure to build-up in the bile duct system.

Your Jefferson medical team brings together the combined expertise of gastroenterologists, hepatologists, radiologists and surgeons to provide personalized care through a multifaceted approach that may include medication therapy or minimally invasive endoscopic procedures, such as endoscopic retrograde cholangiopancreatography (ERCP).

Jefferson physicians are among the most experienced in the Philadelphia region in treating biliary system disorders through minimally invasive endoscopic procedures. Jefferson's Gastrointestinal Endoscopy Unit is one of the busiest academic endoscopy units on the East Coast, where more than 13,000 endoscopic procedures are performed each year.