Jefferson University Hospitals

Pancreas, Biliary & Related Cancer Center

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    Among the Nation's Best for Gastroenterology & GI Surgery
    U.S.News & World Report rated us among the nation's best for Gastroenterology & GI Surgery.
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    Next Day Consultations
    Jefferson Health provides next-day surgical consultations for individuals who require them and wish to see a surgeon quickly.
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The Jefferson Pancreas, Biliary and Related Cancer Center offers a multidisciplinary approach to the diagnosis and treatment of patients with these difficult-to-treat cancers. The Center's internationally renowned experts in treating cancers of the pancreas and biliary tract provide personalized treatment that addresses every aspect of your care.

A team of specialists continually evaluates you throughout your entire course of treatment and brings together the expertise of Jefferson surgeons, oncologists, gastroenterologists, pathologists, pharmacologists, pain management specialists, palliative care specialists and genetics researchers.

Extensive Experience in Performing Pancreatic & Related Surgeries

Surgeons at the Center have extensive experience in performing pancreatic and related surgeries, the success of which clinical studies have shown is significantly improved when performed at high-volume centers such as Jefferson. In a typical year, our surgeons perform approximately 200 pancreatic resections, including more than 120 pancreaticoduodenectomies – commonly referred to as Whipple procedures – and dozens of distal and central pancreatectomies.


Whenever possible, Jefferson surgeons use an innovative procedure called a mini-Whipple that is as effective as the standard procedure while enabling the preservation of the entire stomach and pylorus, and reducing the length of hospital stays and complications.

Leading Pancreatic Cancer Research

Physicians and scientists at the Center are also working to improve the early detection of pancreatic cancer and develop more effective screening procedures. We are leading investigations into genetic, environmental and lifestyle links to pancreatic and related cancers, including a novel approach to individualized therapy based on molecular genetic features of tumors. Our researchers are performing breakthrough studies that are advancing the understanding of the basic biology of pancreatic and related cancers and the molecular mechanisms that underlie the disease process. Our physicians are translating these discoveries into new approaches to patient care.

Center Leadership

    Charles J. Yeo, MD

    Academic Title: Professor
    Samuel D. Gross Professor and Chair of Surgery
    Senior Vice President and Chair, Enterprise Surgery, Jefferson Health
    Co-Director, Pancreas, Biliary and Related Cancer Center

    View Dr. Yeo's profile »