Jefferson University Hospitals

Digestive Health Institute

Celiac Center


In 2011, the Jefferson Celiac Center became Philadelphia’s first celiac disease center. It’s the largest and most integrated provider for your celiac disease in the region.

Our convenient Center City clinic offers a unique advantage over surrounding regions, with two full-time registered dietitians available to help you adapt to the strictly gluten-free diet necessary to improve and manage the lifelong condition.

Our Mission

  • Improve diagnosis and management of celiac disease and associated conditions by centering your care around a core network of specialists
  • Advance scientific knowledge of celiac disease through extensive research and clinical trials
  • Educate physicians, patients and families about celiac disease
  • Support patient advocacy by increasing public awareness

If you’re one of more than 3 million Americans with celiac disease, you know how it feels to be diagnosed. But you also know a confirmed diagnosis comes with a new lifelong commitment to managing your disease. Our clinic offers state-of-the-art technology and advanced research to ensure you’re getting the right care in the right place.

Our compassionate staff understands what it’s like to juggle family meals and sticking to a gluten-free diet. At the Jefferson Celiac Center, your providers will cater to your individual needs, including but not limited to:

Ongoing Expertise in Disease Management

In many cases, adopting a gluten-free diet can help to heal your body but also improve associated symptoms and diseases. You will receive instructions on how to successfully maintain a gluten-free diet from our registered dietician, who is skilled in treating celiac disease. Celiac disease is a chronic autoimmune condition that requires lifelong follow-up. At the Jefferson Celiac Center, you will receive expert guidance in managing your celiac disease, including recommended blood work and a bone density scan.

Comprehensive Care from Multidisciplinary Team of Experts

Celiac disease can affect many other parts of your body besides the intestine, including the hair, skin, glands, liver and bones. To provide you comprehensive care, our gastroenterologists and pathologists collaborate closely, as needed, with specialists who are experienced in treating conditions related to celiac disease. These may include rheumatologists, endocrinologists, dermatologists and oncologists.

Access to Leading-Edge Clinical Trials

Our clinicians and pathologists are engaged in clinical trials open to qualified patients. We offer you the opportunity to participate in scientific studies and clinical trials, involvement that is essential to advancing celiac disease research.

Clinical Trials for Celiac Disease

Symptoms in Non-Celiac Gluten Sensitivity

This study is for people with non-celiac gluten sensitivity (NCGS) who experience gastrointestinal symptoms after consuming gluten. Researchers will evaluate blood, stool and urine markers of gluten ingestion.

Contact study coordinator, Michael Matthews, at 215-503-2545 for more information.

Make an Appointment

To schedule an appointment at the Jefferson Celiac Center, please call 1-800-JEFF-NOW (1-800-533-3669) or schedule an appointment online. 

Center Leadership