Jefferson University Hospitals

Physician Profile

Charles Yeo, MD, FACS

Jefferson University Physician

Academic Title: Professor
Samuel D. Gross Professor of Surgery
Chair, Department of Surgery
Co-Director, Pancreas, Biliary and Related Cancer Center

Surgery - Alimentary Tract
Surgery - Hepato-Pancreatic-Biliary
Surgery - Oncology

Make An Appointment

Click to call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

1100 Walnut Street
5th Floor
Philadelphia PA 19107
Phone: (215) 955-9402
Fax: (215) 923-6609

Medical Services

Years in Practice


Board Certifications

  • Surgery

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital
  • Methodist Hospital Division of Thomas Jefferson University Hospital

Awards and Honors

Philadelphia Magazine's Top Docs 2016,2015,2014,2013,2012,2011,2010,2009

Castle Connolly's America's Top Doctors 2014,2013,2012,2011,2010,2009,2008,2007

Castle Connolly's America's Top Doctors for Cancer 2014,2013,2012,2011,2010


Dr. Yeo completed an advanced GI surgery and vascular surgery fellowship at Johns Hopkins University Hospital. Dr. Yeo received his undergraduate degree at Princeton University.


  • Johns Hopkins University School of Medicine, Medical School


  • Johns Hopkins University Hospital


  • Johns Hopkins University Hospital


  • Johns Hopkins University Hospital
  • SUNY Downstate Medical Center - Brooklyn

Recent Publications

Total parenteral nutrition in patients following pancreaticoduodenectomy: lessons from 1184 patients

Vascular Resections During the Whipple Procedure

Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells

Alterations of type II classical cadherin, cadherin-10 (CDH10), is associated with pancreatic ductal adenocarcinomas

Pancreatic anastomosis after pancreatoduodenectomy: A position statement by the International Study Group of Pancreatic Surgery (ISGPS)

Pneumonia is associated with a high risk of mortality after pancreaticoduodenectomy

The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After

Definition and classification of chyle leak after pancreatic operation: A consensus statement by the International Study Group on Pancreatic Surgery

Invited commentary: Pasireotide and the prevention of pancreatic fistula after pancreatectomy "The continued search for Harry Potter's liquid luck"

Microscopic lymphovascular invasion is an independent predictor of survival in resected pancreatic ductal adenocarcinoma

Cytoplasmic HuR Status Predicts Disease-free Survival in Resected Pancreatic Cancer: A Post-hoc Analysis From the International Phase III ESPAC-3 Clinical Trial

WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner

Modified Appleby Procedure with Arterial Reconstruction for Locally Advanced Pancreatic Adenocarcinoma: A Literature Review and Report of Three Unusual Cases

Hypothyroidism in Pancreatic Cancer: Role of Exogenous Thyroid Hormone in Tumor Invasion - Preliminary Observations

Recurrence and survival after resection of small intraductal papillary mucinous neoplasm-associated Carcinomas (≤ 20-mm invasive component) A multi-institutional analysis

HuR contributes to TRAIL resistance by restricting death receptor 4 expression in pancreatic cancer cells

Delayed Gastric Emptying After Pancreaticoduodenectomy: an Analysis of Risk Factors and Cost

Fluid Restriction During Pancreaticoduodenectomy. Is It Effective in Reducing Postoperative Complications?

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs