Jefferson Health

Physician Profile

Michael Sperling, MD

Jefferson University Physician

Academic Title: Professor
Director, Jefferson Comprehensive Epilepsy Center
Director, Clinical Neurophysiology Laboratory

Neurology - Epilepsy

Make An Appointment

Click to call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

909 Walnut Street
2nd Floor, COB Bldg.
Philadelphia PA 19107
Phone: (215) 955-1222
Fax: (215) 955-0606

Medical Services

Years in Practice


Board Certifications

  • Neurology
  • Clinical Neurophysiology

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital

Awards and Honors

Philadelphia Magazine's Top Docs 2016,2015,2014,2013,2012,2011,2010


  • Temple University School of Medicine, Medical School


  • Mount Sinai Medical Center


  • Mount Sinai Medical Center, NY


  • UCLA Medical Center

Recent Publications

Efficacy, safety, and tolerability of adjunctive brivaracetam for secondarily generalized tonic-clonic seizures: Pooled results from three Phase III studies

Ictal verbal help-seeking: Occurrence and the underlying etiology

Clinical features and postoperative seizure outcome in patients with drug-resistant gelastic seizures without hypothalamic hamartoma

Remote preoperative tonic-clonic seizures do not influence outcome after surgery for temporal lobe epilepsy

Post–epilepsy surgery psychogenic nonepileptic seizures

Complications of subdural and depth electrodes in 269 patients undergoing 317 procedures for invasive monitoring in epilepsy

Seizure clusters in drug-resistant focal epilepsy

Ictal pain: occurrence, clinical features, and underlying etiologies

Spike voltage topography in temporal lobe epilepsy

Seasonality of birth in patients with temporal lobe epilepsy

Patient Historical Risk Factors Associated with Seizure Outcome after Surgery for Drug-Resistant Nonlesional Temporal Lobe Epilepsy

High-frequency brain networks undergo modular breakdown during epileptic seizures

Nonseizure SUDEP: Sudden unexpected death in epilepsy without preceding epileptic seizures

Ictal crying

Clobazam-treated patients with Lennox-Gastaut syndrome experienced fewer seizure-related injuries than placebo patients during trial OV-1012

A reappraisal of mortality after epilepsy surgery

Auras in patients with temporal lobe epilepsy and mesial temporal sclerosis

Historical Risk Factors Associated with Seizure Outcome after Surgery for Drug-Resistant Mesial Temporal Lobe Epilepsy

Gray matter abnormalities in temporal lobe epilepsy: Relationships with resting-state functional connectivity and episodic memory performance

Heart rate and blood pressure in sudden unexpected death in epilepsy (SUDEP)