Jefferson Health

Physician Profile

Michael Sperling, MD

Jefferson University Physician

Academic Title: Professor
Director, Jefferson Comprehensive Epilepsy Center
Director, Clinical Neurophysiology Laboratory

Neurology - Epilepsy

Make An Appointment

Click to call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

909 Walnut Street
2nd Floor, COB Bldg.
Philadelphia PA 19107
Phone: (215) 955-1222
Fax: (215) 955-0606

Medical Services

Years in Practice


Board Certifications

  • Neurology
  • Clinical Neurophysiology

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital

Awards and Honors

Philadelphia Magazine's Top Docs 2016,2015,2014,2013,2012,2011,2010


  • Temple University School of Medicine, Medical School


  • Mount Sinai Medical Center


  • Mount Sinai Medical Center, NY


  • UCLA Medical Center

Recent Publications

Postsurgical outcome in patients with olfactory auras and drug-resistant epilepsy

Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy for Treatment of Drug-Resistant Epilepsy

Mesial temporal lobe epilepsy with childhood febrile seizure

Postsurgical outcome in patients with auditory auras and drug-resistant epilepsy

The Temporal Instability of Resting State Network Connectivity in Intractable Epilepsy

Longitudinal qualitative characterization of mri features after laser interstitial thermal therapy in drug-resistant epilepsy

Direct Electrical Stimulation of the Human Entorhinal Region and Hippocampus Impairs Memory

Efficacy, safety, and tolerability of adjunctive brivaracetam for secondarily generalized tonic-clonic seizures: Pooled results from three Phase III studies

Clinical features and postoperative seizure outcome in patients with drug-resistant gelastic seizures without hypothalamic hamartoma

Ictal verbal help-seeking: Occurrence and the underlying etiology

Remote preoperative tonic-clonic seizures do not influence outcome after surgery for temporal lobe epilepsy

Post–epilepsy surgery psychogenic nonepileptic seizures

Complications of subdural and depth electrodes in 269 patients undergoing 317 procedures for invasive monitoring in epilepsy

Seizure clusters in drug-resistant focal epilepsy

Ictal pain: occurrence, clinical features, and underlying etiologies

Spike voltage topography in temporal lobe epilepsy

Seasonality of birth in patients with temporal lobe epilepsy

Patient Historical Risk Factors Associated with Seizure Outcome after Surgery for Drug-Resistant Nonlesional Temporal Lobe Epilepsy

High-frequency brain networks undergo modular breakdown during epileptic seizures

Nonseizure SUDEP: Sudden unexpected death in epilepsy without preceding epileptic seizures