Jefferson University Hospitals

Physician Profile


Nicholas Ruggiero, II, MD, FACP, FACC, FSCAI, FSVM, FCPP

Jefferson University Physician

Academic Title: Associate Professor
Director, Structural Heart Disease and Non-Coronary Interventions
Director, Jefferson Heart Institute Vascular Laboratory
Associate Director, Cardiovascular Diseases Fellowship

Cardiology - Interventional Cardiology

Make An Appointment

Click to call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

Gibbon Bldg., Ste 6210
111 S. 11th Street
Philadelphia PA 19107
Phone: (215) 955-5050
Fax: (215) 503-5874

Medical Services

Years in Practice


Board Certifications

  • Interventional Cardiology
  • Cardiovascular Disease
  • Internal Medicine
  • Echocardiography
  • Nuclear Cardiology

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital

Awards and Honors

SCAI Gregory Braden Interventional Cardiology Fellow of the Year Recipient 2010


Dr. Ruggiero's subspecialties include: Valvular Heart Disease, Structural Heart Disease and Interventions and Vascular Medicine and Interventions.

Personal Statement

Dr. Ruggiero's expertise includes Valvular Heart Disease (valvuloplasty and percutaneous valve implantation), Structural Heart Disease and Interventions (ASD, PFO and left atrial appendage closure) Vascular Medicine and Interventions (including carotid artery stenting and complex peripheral interventions) complex coronary interventions and clinical research.


  • Jefferson Medical College, Medical School


  • Thomas Jefferson University Hospital


  • Thomas Jefferson University Hospital


  • Massachusetts General Hospital, Boston, MA

Recent Publications

Non-Invasive Intra-cardiac Pressure Measurements Using Subharmonic-Aided Pressure Estimation: Proof of Concept in Humans

Automated and Manual Measurements of the Aortic Annulus with ECG-Gated Cardiac CT Angiography Prior to Transcatheter Aortic Valve Replacement: Comparison with 3D-Transesophageal Echocardiography

Importance of adjunct delivery techniques to optimize deployment success of distal protection filters during vein graft intervention

PFO and cryptogenic stroke: Do we finally have closure?

An update on management of the patient presenting with non-ST-elevation acute coronary syndromes

Frequency of use of statins and aspirin in patients with previous coronary artery bypass grafting

Acute Myocardial Infarction Complicated by Cardiogenic Shock: An Algorithm-Based Extracorporeal Membrane Oxygenation Program Can Improve Clinical Outcomes

A call to arms: Radial artery access for percutaneous coronary intervention

Carotid artery stenting for recurrent carotid artery restenosis after previous ipsilateral carotid artery endarterectomy or stenting: A report from the National Cardiovascular Data Registry

Renal denervation revisited: Complexity following symplicity

"very" very late stent thrombosis: Acute myocardial infarction from drug-eluting stent thrombosis more than 5 years after implantation

Outcomes of carotid endarterectomy in the elderly: Report from the national cardiovascular data registry

Saphenous vein graft disease: Review of pathophysiology, prevention, and treatment

Modern antiplatelet agents in coronary artery disease.

Revascularization in renal artery stenosis

Carotid and vertebral intervention

Endovascular management of acute limb ischemia

Carotid stent fracture and restenosis management

Carotid revascularization immediately before urgent cardiac surgery: Practice patterns associated with the choice of carotid artery stenting or endarterectomy: A report from the CARE (Carotid Artery Revascularization and Endarterectomy) registry

The current management of aortic, common iliac, and external iliac artery disease: Basic data underlying clinical decision making