Jefferson University Hospitals

Physician Profile

A.M. Rostami, MD, PhD

Jefferson University Physician

Academic Title: Professor
Chair, Department of Neurology

Specialties
Neurology - Neuroimmunology

Make An Appointment

Click to call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

Philadelphia
909 Walnut Street
2nd Floor, COB Bldg.
Philadelphia PA 19107
Phone: (215) 955-1234
Fax: (215) 955-1390

Medical Services

Board Certifications

  • Neurology

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital
  • Methodist Hospital Division of Thomas Jefferson University Hospital

Notes

Subspecialty is Multiple Sclerosis

Education

  • Shiraz University, Medical School

Residency

  • Hospital of the University of Pennsylvania

Fellowship

  • Hospital of the University of Pennsylvania

Conditions

Recent Publications

DAB389IL-2 recombinant fusion toxin effect on lymphocyte- and macrophage-producing cytokine subpopulation cells in experimentally induced demyelinating disease in mice

Induction of peripheral tolerance in ongoing autoimmune inflammation requires interleukin 27 signaling in dendritic cells

LPS-treated bone marrow-derived dendritic cells induce immune tolerance through modulating differentiation of CD4+regulatory T cell subpopulations mediated by 3G11 and CD127

1,25-Dihydroxyvitamin D3suppressed experimental autoimmune encephalomyelitis through both immunomodulation and oligodendrocyte maturation

Selective depletion of CD11c+CD11b+dendritic cells partially abrogates tolerogenic effects of intravenous MOG in murine EAE

Galectin-1 is essential for the induction of MOG35–55-based intravenous tolerance in experimental autoimmune encephalomyelitis

IL-12Rβ2 has a protective role in relapsing-remitting experimental autoimmune encephalomyelitis

Apoptotic cell-treated dendritic cells induce immune tolerance by specifically inhibiting development of CD4+effector memory T cells

IL-9 signaling affects central nervous system resident cells during inflammatory stimuli

Emerging immunopharmacological targets in multiple sclerosis

1,25-Dihydroxyvitamin D3 enhances neural stem cell proliferation and oligodendrocyte differentiation

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs

c-kit plays a critical role in induction of intravenous tolerance in experimental autoimmune encephalomyelitis

Mechanisms of immunological tolerance in central nervous system inflammatory demyelination

Granulocyte-macrophage colony-stimulating factor in central nervous system autoimmunity

Silencing IFN-γ binding/signaling in astrocytes versus microglia leads to opposite effects on central nervous system autoimmunity

Expression of GM-CSF in T cells is increased in multiple sclerosis and suppressed by IFN-β therapy

Astrocyte-derived lactosylceramide implicated in multiple sclerosis

Interferon regulatory factor (IRF) 3 is critical for the development of experimental autoimmune encephalomyelitis

Tolerogenic dendritic cells produced by lentiviral-mediated CD40- and interleukin-23p19-specific shRNA can ameliorate experimental autoimmune encephalomyelitis by suppressing T helper type 17 cells