Jefferson University Hospitals

Provider Profile

William M. Keane, MD

Jefferson University Physician

Academic Title: Professor
Chair, Department of Otolaryngology - Head and Neck Surgery
Co-Director, Jefferson Center for Head and Neck Surgery

Otolaryngology/Head & Neck Surgery
Otolaryngology/Head & Neck Surgery - General
Otolaryngology/Head & Neck Surgery - Head & Neck Cancers
Otolaryngology/Head & Neck Surgery - Thyroid/Parathyroid

Make An Appointment

Click to call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

925 Chestnut Street
6th Floor
Philadelphia PA 19107
Phone: (215) 955-6760
Fax: (215) 503-3736

Medical Services

Years in Practice


Board Certifications

  • Otolaryngology

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital
  • Methodist Hospital Division of Thomas Jefferson University Hospital

Awards and Honors

Philadelphia Magazine's Top Docs 2016,2015,2014,2013,2012,2011,2010


  • Harvard University, Medical School


  • University of Rochester Medicine & Dentistry
  • Strong Memorial Hospital, Rochester, NY


  • Hospital of the University of Pennsylvania

Jefferson physicians accept most health insurance plans, including those listed below. However, plan acceptance may vary by practice and may be subject to change. If you have questions about whether a specific physician accepts your insurance, please contact your insurance company.

Insurances Accepted

  • Aetna
  • Aetna PA Employee Benefit Trust Fund (PEBTF)
  • Amer Assoc Retired Persons (AARP)
  • AmeriHealth
  • Amerihealth Caritas
  • AmeriHealth Comprehensive
  • AmeriHealth HMO
  • AmeriHealth Major Medical
  • AmeriHealth Personal Choice
  • BC BS Special Care
  • Blue Choice
  • Blue Cross/Blue Shield
  • Blue Cross/Blue Shield of Delaware
  • Cigna Healthspring
  • Cigna PPO, POS
  • Consumer Health Network PPO
  • CorVel
  • Coventry/Health America
  • Delaware Blue Cross/Blue Shield
  • Devon
  • Empire BC/BS
  • Employers Health Network PPO
  • Evolutions (Guardian Resources)
  • Federal BCBS
  • First Health Network
  • Galaxy
  • Geisinger Health Plan
  • Health America PPO
  • Health Management Network PPO
  • Horizon Blue Cross/Blue Shield
  • Horizon HMO
  • HumanaChoicePPO,Medicare,GoldPlusHMO
  • Inter-County Health Plan
  • Intergroup Preferred
  • Jeff Plus
  • Keystone 65 HMO
  • Keystone First VIP Choice
  • Keystone First/Connect
  • Keystone Health Plan East
  • Medallion of New Jersey
  • Medicaid of PA
  • Medicare
  • Mercy LIFE
  • MultiPlan Inc.
  • NJ Blue Shield
  • NJ Plus
  • Oxford of PA
  • Personal Choice (GPPPN)
  • Personal Choice 65
  • PlanCare America
  • Postal Workers/Mailhandlers
  • PPO Next
  • Preferred Care PPO
  • Premier Blue
  • Prime Health Services, Inc.
  • Private Healthcare Systems (PHCS)
  • Qualcare
  • Tricare
  • United Healthcare
  • UPMC HMO,PPO ReadingHspEmpONLY
  • UPMC Medicare HMO
  • US Family Health Plan

Recent Publications

Safety and efficacy of functional laryngectomy for end-stage dysphagia

Tumor Metabolism in the Microenvironment of Nodal Metastasis in Oral Squamous Cell Carcinoma

Positron emission tomography/computed tomography after primary transoral robotic surgery for oropharyngeal squamous cell carcinoma

Pathologic Markers in Surgically Treated HPV-Associated Oropharyngeal Cancer: Retrospective Study, Systematic Review, and Meta-analysis

Prospective, randomized, controlled trial using best-selling smoking-cessation book

Multicompartment metabolism in papillary thyroid cancer

Phase I Trial Using Induction Ciplatin, Docetaxel, 5-FU and Erlotinib Followed by Cisplatin, Bevacizumab and Erlotinib With Concurrent Radiotherapy for Advanced Head and Neck Cancer

Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-Analysis

Effectiveness of PET/CT in the preoperative evaluation of neck disease

Value of fluoro-2-deoxy-D-glucose-positron emission tomography for detecting metastatic lesions in head and neck cancer

Localized oropharyngeal amyloidosis

The use of a covered stent in carotid blowout syndrome

Laryngeal alveolar rhabdomyosarcoma involving the true vocal fold in an adult: Case report

Prevalence of complementary and alternative medicine use among a population of head and neck cancer patients: A survey-based study

Daily Image Guidance With Cone-Beam Computed Tomography for Head-and-Neck Cancer Intensity-Modulated Radiotherapy: A Prospective Study

Correlation of positron emission tomography with fine needle aspiration biopsies in head and neck malignancy

Pretreatment FDG-PET standardized uptake value as a prognostic factor for outcome in head and neck cancer

Superficial musculoaponeurotic system elevation and fat graft reconstruction after superficial parotidectomy

Management of the Neck in Differentiated Thyroid Cancer

Ultrasound-guided contrast-enhanced sentinel node biopsy of the head and neck in a porcine model