Jefferson University Hospitals

Physician Profile

Renato Iozzo, MD

Jefferson University Physician

Academic Title: Professor
Director, Electron Microscopy

Pathology - Electron Microscopy

Make An Appointment

Click to call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

336 Jefferson Alumni Hall
1020 Locust Street
Philadelphia PA 19107
Phone: (215) 503-2208

Medical Services

Board Certifications

  • Pathology

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital
  • Methodist Hospital Division of Thomas Jefferson University Hospital


  • Univ di Firenze, Italy, Medical School

Recent Publications

A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia

Steroid hormones are key modulators of tissue mechanical function via regulation of collagen and elastic fibers

Decorin-inducible Peg3 evokes beclin 1-mediated autophagy and thrombospondin 1-mediated angiostasis

Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin

Decorin is a devouring proteoglycan: Remodeling of intracellular catabolism via autophagy and mitophagy

Decorin-evoked paternally expressed gene 3 (PEG3) is an upstream regulator of the transcription factor EB (TFEB) in endothelial cell autophagy

Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology

The nature and biology of basement membranes

A current view of perlecan in physiology and pathology: A mosaic of functions

c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes

The perlecan-interacting growth factor progranulin regulates ubiquitination, sorting, and lysosomal degradation of sortilin

Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium

The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis

Decorin and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons

Oncogenic activin C interacts with decorin in colorectal cancer in vivo and in vitro

Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

Endorepellin-evoked autophagy contributes to angiostasis

Decorin interacting network: A comprehensive analysis of decorin-binding partners and their versatile functions

αvβ6 integrin promotes castrate-resistant prostate cancer through JNK1-mediated activation of androgen receptor

Mechanisms of progranulin action and regulation in genitourinary cancers