Jefferson Health

Physician Profile

Karen Gripp, MD

Academic Title: Professor

Specialties
Pediatrics - Medical Genetics

Make An Appointment

Click to call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

Wilmington
duPont Hospital for Children
1600 Rockland Road
Wilmington DE 19803
Phone: (302) 651-5916

Medical Services

Board Certifications

  • Pediatrics
  • Clinical Genetics
  • Clinical Molecular Genetics

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital

Awards and Honors

Philadelphia Magazine's Top Docs 2016

Education

  • University of Hamburg, Medical School

Internship

  • Thomas Jefferson University Hospital

Residency

  • Thomas Jefferson University Hospital

Fellowship

  • Children's Hospital of Philadelphia

Conditions

Recent Publications

Age-related differences in prevalence of autism spectrum disorder symptoms in children and adolescents with Costello syndrome

Phenotypic spectrum of Costello syndrome individuals harboring the rare HRAS mutation p.Gly13Asp

Cytotoxicity of zardaverine in embryonal rhabdomyosarcoma from a Costello syndrome patient

A novel patient with an attenuated Costello syndrome phenotype due to an HRAS mutation affecting codon 146—Literature review and update

Attenuated phenotype of Costello syndrome and early death in a patient with an HRAS mutation (c.179G>T; p.Gly60Val) affecting signalling dynamics

Constitutional LZTR1 mutation presenting with a unilateral vestibular schwannoma in a teenager

The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies

Paternal uniparental disomy with segmental loss of heterozygosity of chromosome 11 are hallmark characteristics of syndromic and sporadic embryonal rhabdomyosarcoma

Nephroblastomatosis or Wilms tumor in a fourth patient with a somatic PIK3CA mutation

A novel rasopathy caused by recurrent de novo missense mutations in PPP1CB closely resembles Noonan syndrome with loose anagen hair

The Fourth International Symposium on Genetic Disorders of the Ras/MAPK pathway

36th Annual David W. Smith Workshop on Malformations and Morphogenesis: Abstracts of the 2015 annual meeting

The role of objective facial analysis using FDNA in making diagnoses following whole exome analysis. Report of two patients with mutations in the BAF complex genes

Maternal uniparental disomy of chromosome 20: A novel imprinting disorder of growth failure

Paternal uniparental disomy 11p15.5 in the pancreatic nodule of an infant with Costello syndrome: Shared mechanism for hyperinsulinemic hypoglycemia in neonates with Costello and Beckwith-Wiedemann syndrome and somatic loss of heterozygosity in Costello syndrome driving clonal expansion

Mutations in RIT1 cause Noonan syndrome - additional functional evidence and expanding the clinical phenotype

Mandibulofacial Dysostosis with Microcephaly: Mutation and Database Update

PIAS4 is associated with macro/microcephaly in the novel interstitial 19p13.3 microdeletion/microduplication syndrome

Differentiating between copy-number-variation and gain-of-function mutation

High Incidence of Noonan Syndrome Features Including Short Stature and Pulmonic Stenosis in Patients carrying NF1 Missense Mutations Affecting p.Arg1809: Genotype-Phenotype Correlation