Jefferson University Hospitals

Physician Profile

Claudia Gragnoli, MD, PhD

Jefferson University Physician

Endocrinology/Diabetes & Metabolism
Endocrinology/Diabetes & Metabolism - Thyroid & Parathyroid
Endocrinology/Diabetes & Metabolism - Weight Management

Appointment Scheduling

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Existing Patients

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More Ways to Get in Touch

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Office Locations

Walnut Towers, Suite 600
211 S. 9th Street
Philadelphia PA 19107
Phone: (215) 955-1925
Fax: (215) 928-3160
Methodist Hospital
2301 South Broad Street
Philadelphia PA 19148
Phone: (215) 952-5050

Medical Services

Years in Practice


Board Certifications

  • Endocrinology, Diabetes & Metabolism
  • Internal Medicine

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital
  • Methodist Hospital Division of Thomas Jefferson University Hospital


  • University of Rome Tor Vergata, Italy, Medical School


  • University of La Sapienza, Italy


  • University of La Sapienza, Italy


  • University of La Sapienza, Italy

Recent Publications

Integrating Evolutionary Game Theory into Mechanistic Genotype-Phenotype Mapping

Dopamine-prolactin pathway potentially contributes to the schizophrenia and type 2 diabetes comorbidity

T2D and Depression Risk Gene Proteasome Modulator 9 is Linked to Insomnia

Hypothesis of the neuroendocrine cortisol pathway gene role in the comorbidity of depression, type 2 diabetes, and metabolic syndrome

Proteasome modulator 9 gene SNPs, responsible for anti-depressant response, are in linkage with generalized anxiety disorder

Overweight condition and waist circumference and a candidate gene within the 12q24 locus

Proteasome modulator 9 and depression in type 2 diabetes

Proteasome modulator 9 is linked to microvascular pathology of T2D

Potential role of prolactin in antipsychotic-mediated association of schizophrenia and type 2 diabetes

Depression and type 2 diabetes: Cortisol pathway implication and investigational needs

Proteasome modulator 9 gene is linked to diabetic and non-diabetic retinopathy in T2D

Proteasome modulator 9 and carpal tunnel syndrome

PSMD9 is linked to type 2 diabetes neuropathy

Proteasome Modulator 9 SNPs are linked to hypertension in type 2 diabetes families

T2D-nephropathy linkage within 12q24 locus

Hypercholesterolemia and a candidate gene within the 12q24 locus

Proteasome modulator 9 and macrovascular pathology of T2D

PSMD9 is linked to MODY3

PSMD9 gene in the NIDDM2 locus is linked to type 2 diabetes in Italians

CDK4 IVS4-nt40G→A and T2D-associated obesity in Italians rapid communication