Jefferson University Hospitals

Provider Profile

Claudia Gragnoli, MD, PhD

Jefferson University Physician

Endocrinology/Diabetes & Metabolism
Endocrinology/Diabetes & Metabolism - Thyroid & Parathyroid
Endocrinology/Diabetes & Metabolism - Weight Management

Appointment Scheduling

Call 1-800-JEFF-NOW

Existing Patients

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New Patients  | Online Scheduling

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More Ways to Get in Touch

Call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

Walnut Towers, Suite 600
211 S. 9th Street
Philadelphia PA 19107
Phone: (215) 955-1925
Fax: (215) 928-3160
Methodist Hospital
2301 South Broad Street
Philadelphia PA 19148
Phone: (215) 952-5050

Medical Services

Years in Practice


Board Certifications

  • Endocrinology, Diabetes & Metabolism
  • Internal Medicine

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital
  • Methodist Hospital Division of Thomas Jefferson University Hospital


  • University of Rome Tor Vergata, Italy, Medical School


  • University of La Sapienza, Italy


  • University of La Sapienza, Italy


  • University of La Sapienza, Italy

Recent Publications

Seasonality of blood neopterin levels in the Old Order Amish

Sleep onset insomnia, daytime sleepiness and sleep duration in relationship to Toxoplasma gondii IgG seropositivity and serointensity

Integrating Evolutionary Game Theory into Mechanistic Genotype-Phenotype Mapping

Dopamine-prolactin pathway potentially contributes to the schizophrenia and type 2 diabetes comorbidity

T2D and Depression Risk Gene Proteasome Modulator 9 is Linked to Insomnia

Hypothesis of the neuroendocrine cortisol pathway gene role in the comorbidity of depression, type 2 diabetes, and metabolic syndrome

Proteasome modulator 9 gene SNPs, responsible for anti-depressant response, are in linkage with generalized anxiety disorder

Overweight condition and waist circumference and a candidate gene within the 12q24 locus

Proteasome modulator 9 and depression in type 2 diabetes

Proteasome modulator 9 is linked to microvascular pathology of T2D

Potential role of prolactin in antipsychotic-mediated association of schizophrenia and type 2 diabetes

Depression and type 2 diabetes: Cortisol pathway implication and investigational needs

Proteasome modulator 9 and carpal tunnel syndrome

Proteasome modulator 9 gene is linked to diabetic and non-diabetic retinopathy in T2D

PSMD9 is linked to type 2 diabetes neuropathy

Proteasome Modulator 9 SNPs are linked to hypertension in type 2 diabetes families

T2D-nephropathy linkage within 12q24 locus

Hypercholesterolemia and a candidate gene within the 12q24 locus

Proteasome modulator 9 and macrovascular pathology of T2D

PSMD9 is linked to MODY3