Jefferson University Hospitals

Physician Profile

Seyfettin Alpdogan, MD

Jefferson University Physician

Academic Title: Associate Professor

Hematology - Medical Oncology
Medical Oncology
Medical Oncology - Bone Marrow Transplant
Medical Oncology - Hematologic Malignancies
Medical Oncology - Leukemia/Lymphoma

Make An Appointment

Click to call 1-800-JEFF-NOW (800-533-3669) or

Office Locations

925 Chestnut Street
Suite 420A
Philadelphia PA 19107
Phone: (215) 955-8874
Fax: (215) 955-2340

Medical Services

Board Certifications

  • Internal Medicine

Hospital Affiliation / Admitting Privileges

  • Thomas Jefferson University Hospital
  • Methodist Hospital Division of Thomas Jefferson University Hospital


Dr. Alpdogan also specializes in stem cell transplantation.


  • Hacettepe University, Ankara, Turkey, Medical School


  • Haseki State University
  • Marmara University Hospital


  • Memorial Sloan-Kettering Cancer Center
  • Yale-New Haven Hospital , New Haven, CT

Recent Publications

TNF activity and T cells

Dynamics of M1 macrophages in oral mucosal lesions during the development of acute graft-versus-host disease in rats

Divergent effects of Wnt/β-catenin signaling modifiers on the preservation of human limbal epithelial progenitors according to culture condition

Therapeutic effects of STAT3 inhibition by nifuroxazide on murine acute graft graft-vs.-host disease: Old drug, new use

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity

Choosing the Alternative

Inhibition of 5-lipoxygenase alleviates graft-versus-host disease

Altered expression of TRAIL on mouse T cells via ERK phosphorylation by Rhodiola rosea L. and its marker compounds

STAT3 Expression in Host Myeloid Cells Controls Graft-versus-Host Disease Severity

A new tool for rapid and reliable diagnosis of HLA loss relapses after HSCT

Treatment of rare cutaneous T‑cell lymphoma and blastic plasmacytoid dendritic cell neoplasm | Therapie seltener kutaner T‑Zell-Lymphome und der blastären plasmazytoiden dendritischen Zellneoplasie

Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease

Early recovery of T-cell function predicts improved survival after T-cell depleted allogeneic transplant

Associations between acute GVHD-related biomarkers and endothelial cell activation after allogeneic hematopoietic stem cell transplantation

Depletion-Resistant CD4 T Cells Enhance Thymopoiesis During Lymphopenia

Predictive Value of Clinical Findings and Plasma Biomarkers after Fourteen Days of Prednisone Treatment for Acute Graft-versus-host Disease

FLT3 ligand regulates thymic precursor cells and hematopoietic stem cells through interactions with CXCR4 and the marrow niche

Glycosylation and oligomeric state of envelope protein might influence HIV-1 virion capture by α4β7 integrin

CD49d associates with nodal presentation and subsequent development of lymphadenopathy in patients with chronic lymphocytic leukaemia

Host-derived CD70 suppresses murine graft-versus-host disease by limiting donor T cell expansion and effector function