PMP (Pseudomyxoma Peritone)
PMP, or pseudomyxoma peritonei, is a rare disease characterized by the presence of mucin-producing tumors in the abdominal cavity. For many, the disease does not exhibit symptoms until it reaches a relatively advanced stage.
Although there is no known underlying cause of PMP, the most common source of the tumors is from appendiceal (appendix) cancer. It generally develops as a small polyp-like growth, or adenoma, then breaks or tears through the appendix, spreading mucin throughout the peritoneum — the thin membrane that lines the abdominal and pelvic cavities.
The condition is most often discovered during surgery for other conditions such as hernia repair. To diagnose PMP, your Jefferson physician may request a CT scan of the chest, abdomen and pelvis; exploratory laparoscopy; and blood tests.
Jefferson specialists trained in treating this condition may perform a specialized cytroreductive surgery (CRS) to attempt to remove all of the tumors and affected tissues. A preventive postoperative systemic chemotherapy may also be recommended.