Jefferson Health

Open Clinical Trials at the Marcus Institute of Integrative Health

Pilot Research Study of the Effect of Anti-Oxidant Supplementation with N-Acetyl Cysteine in Breast Cancer
IRB Protocol # 12D.396
The purpose of this study is to determine whether or not there are measurable effects on breast tumors in response to a very strong anti-oxidant called N-Acetyl Cysteine (or NAC) in women with stage 0/I breast cancer.

Phase I/II Study of Intravenous Vitamin C in Combination with Irinotecan Versus Irinotecan Alone for Advanced Colorectal Cancer
IRB Protocol # 11D.459
The purpose is to determine whether participants receiving standard chemotherapy of Irinotecan for recurrent or advanced colorectal cancer plus high doses of Vitamin C will be safe and well tolerated, and whether this combination is more beneficial compared to Irinotecan alone. The goal is also to assess its effect on the cancer.

Assessing the Efficacy and Safety of Intravenous Vitamin C in Combination with Standard Chemotherapy for Pancreatic Cancer
IRB Protocol # 11D.365
The purpose of this study is to determine whether participants receiving a standard chemotherapy of gemcitabine and erlotnib for pancreatic cancer with high doses of Vitamin C will be beneficial and well tolerated. The primary goal is to better evaluate the response to the dosage and combination of therapies and confirm the initial safety data collected in Phase I.

Reducing the Stress of Unpleasant Thoughts and Memories of Cancer Experiences
IRB Protocol # 09D.182
The purpose of this study is to evaluate if a new stress-reduction technique called Neuro-Emotional Technique (or NET) can reduce these distressing recollections among cancer patients. NET is a brief two-to-five session intervention involving cognitive and behavioral techniques from psychology, a biofeedback technique called the muscle test and sometimes traditional Chinese acupuncture.

A Study of Vitamin C in the Treatment of Metastatic Hepatocellular Carcinoma
IRB Protocol # 12D.424
The purpose of this clinical trial is to study an intravenous Vitamin C treatment for people with metastatic hepatocellular carcinoma, who are also receiving sorafenib, to see whether the combination treatment of ascorbic acid and sorafenib is safe and well tolerated. The goal is to utilize CT scans to assess overall tumor response rate as well as evaluate disease progression.

Characteristics of Patients Presenting to Integrative Medicine Centers
IRB Protocol # 08D.205
The Jefferson-Myrna Brind Center of Integrative Medicine is one of eight centers that make up the Bravewell Integrative Medicine Research Network (or BraveNet). The main goal of BraveNet is to evaluate integrative medicine approaches through cross-sectional and longitudinal collection of data in patient characteristics, utilization patterns, safety, effectiveness and costs.